This paper aims at proposing tractable algorithms to find effectively good solutions to large size chance-constrained combinatorial problems. A new robust model is introduced to deal with uncertainty in mixed-integer linear problems. It is shown to be strongly related to chance-constrained programming when considering pure 0-1 problems. Furthermore, its tractability is highlighted. Then, an optimization algorithm is designed to provide possibly good solutions to chance-constrained combinatorial problems. This approach is numerically tested on knapsack and multi-dimensional knapsack problems. The results obtained outperform many methods based on earlier literature.