Robust optimization of dose-volume metrics for prostate HDR-brachytherapy incorporating target- and OAR volume delineation uncertainties
In radiation therapy planning, uncertainties in target volume definition yield a risk of underdosing the tumor. The classical way to prevent this in the context of external beam radiotherapy (EBRT) has been to expand the clinical target volume (CTV) with an isotropic margin to obtain the planning target volume (PTV). However, the EBRT-based PTV concept … Read more