adverse drug reactions/events

A continuous GRASP to determine the relationship between drugs and adverse reactions

  • Michael J. Hirsch
  • Claudio N. Meneses
  • Panos M. Pardalos
  • Mauricio G.C. Resende
  • M. A. Ragle
    • Categories Biomedical Applications, Meta Heuristics, Stochastic Approaches Tags , , , , , , ,

    Adverse drug reactions (ADRs) are estimated to be one of the leading causes of death. Many national and international agencies have set up databases of ADR reports for the express purpose of determining the relationship between drugs and adverse reactions that they cause. We formulate the drug-reaction relationship problem as a continuous optimization problem and … Read more