Characterizing Rational Transplant Program Response to Outcome-Based Regulation

Organ transplantation is an increasingly common therapy for many types of end-stage organ failure, including lungs, hearts, kidneys and livers. The past twenty years have seen increased scrutiny of post-transplant outcomes in the United States, in order to ensure the efficient utilization of the scarce organ supply. Under regulations by the Organ Procurement Transplantation Network … Read more

Data-Driven Ranges of Near-Optimal Actions for Finite Markov Decision Processes

Markov decision process (MDP) models have been used to obtain non-stationary optimal decision rules in various applications, such as treatment planning in medical decision making. However, in practice, decision makers may prefer other strategies that are not statistically different from the optimal decision rules. To benefit from the decision makers’ expertise and provide flexibility in … Read more