We present an exact algorithm for mean-risk optimization subject to a budget constraint, where decision variables may be continuous or integer. The risk is measured by the covariance matrix and weighted by an arbitrary monotone function, which allows to model risk-aversion in a very individual way. We address this class of convex mixed-integer minimization problems by designing a branch-and-bound algorithm, where at each node, the continuous relaxation is solved by a non-monotone Frank-Wolfe type algorithm with away-steps. Experimental results on portfolio optimization problems show that our approach can outperform the MISOCP solver of CPLEX 12.6 for instances where a linear risk-weighting function is considered.
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