Portfolio optimization is an ongoing hot topic of mathematical optimization and management science. Due to the current financial market environment with low interest rates and volatile stock markets, it is getting more and more important to extend portfolio optimization models by other types of investments than classical assets. In this paper, we present a mixed-integer multistage stochastic model that includes investment opportunities in irreversible and long-term infrastructure projects in the context of renewable energies, which are also subject to policy risk. On realistic time scales for investment problems of this type, the resulting instances are by far too large to be solved with today’s most evolved optimization software. Thus, we present a tailored moving-horizon approach together with suitable approximations and simplifications of the model. We evaluate these approximations and simplifications in a computational sensitivity analysis and derive a final model that can be tackled on a realistic instance by our moving-horizon approach.