Strategy Investments in Matrix Games

We propose an extension of matrix games where the row player may select rows and remove columns, subject to a budget constraint. We present an exact mixed-integer linear programming (MILP) formulation for the problem, provide analytical results concerning its solution, and discuss applications in the security domain. Our computational experiments show heuristic approaches on average … Read more

Combination Chemotherapy Optimization

Chemotherapy is one of the primary modalities of cancer treatment. Chemotherapy drug administration is a complex problem that often requires expensive clinical trials to evaluate potential regimens. One way to alleviate this burden and better inform future trials is to build reliable models for drug administration. Previous chemotherapy optimization models have mainly relied on optimal … Read more