decision support

A Decision-Support Framework for Structuring and Reducing Large Multi-Objective Solution Sets via Clustering: An Application to Proton Therapy

Categories (Mixed) Integer Linear Programming, Biomedical Applications, Multi-Criteria Optimization Tags , , , , , , , , , , ,

This paper proposes a four-stage decision-support framework for structuring and reducing large multi-objective solution sets into compact and interpretable collections of representative alternatives. The methodology combines: (Phase 1) systematic solution generation through extended goal programming and structured preference exploration; (Phase 2) robustness-aware enrichment and profiling under weight sensitivity analysis; (Phase 3) filtering and dominance-based reduction … Read more

Sensitivity-based decision support for critical measures using the example of COVID-19 dynamics

Categories Applications - OR and Management Sciences, Optimization of Simulated Systems, Other Topics Tags , , , ,

We parametrize public policies in the context of the COVID-19 pandemic to evaluate the effectiveness of policies through sensitivity-based methods in order to offer insights into understanding the contributions to critical measures in retrospective. The study utilizes a group-specific SEIR model with a tracing and isolation strategy and vaccination programs. Public policies are applied to … Read more

Expert-Enhanced Machine Learning for Cardiac Arrhythmia Classification

Categories Biomedical Applications, Combinatorial Optimization Tags , , , , ,

We propose a new method for the classification task of distinguishing atrial Fibrillation (AFib) from regular atrial tachycardias including atrial Flutter (AFlu) on the basis of a surface electrocardiogram (ECG). Although recently many approaches for an automatic classification of cardiac arrhythmia were proposed, to our knowledge none of them can distinguish between these two. We … Read more