Continuous optimization of beamlet intensities for photon and proton radiotherapy

Inverse approaches and, in particular, intensity modulated radiotherapy (IMRT), in combination with the development of new technologies such as multi-leaf collimators (MLCs), have enabled new potentialities of radiotherapy for cancer treatment. The main mathematical tool needed in this connection is numerical optimization. In this article, the variety of continuous optimization approaches, which have been proposed … Read more