resource-constrained scheduling

Integer Optimization Model and Algorithm for the Stem Cell Culturing Problem

  • Jinil Han
  • Kyungsik Lee
  • Jongyoon Park
    • Categories (Mixed) Integer Linear Programming, Applications - OR and Management Sciences Tags , , ,

    In this paper, we present a novel scheduling problem, the stem cell culturing problem (SCP), which is identified in an attempt to improve the productivity of a manufacturing system producing a commercialized autologous stem cell therapeutic product for treating an incurable disease. For a given therapeutic product along with the corresponding manufacturing process, which is … Read more

    Steiner tree network scheduling with opportunity cost of time

  • Fabien Cornillier
    • Categories Facility Planning and Design, Network Optimization, Scheduling Tags , ,

    This paper points out the impact of opportunity cost of time (high discount rate or high rate of time preference, time-dependent profits, etc.) in designing real-world Steiner trees like electricity, gas, water, or telecommunications networks. We present the Steiner Tree Scheduling Problem which consists of finding a Steiner tree in an activity-on-arc graph that spans … Read more