The multiphase course timetabling problem

This paper introduces the multiphase course timetabling problem and presents mathematical formulations and effective solution algorithms to solve it in a real case study. Consider a pool of lessons and a number of students who are required to take a subset of these lessons to graduate. Each lesson consists of a predetermined and consecutive sequence … Read more

Branch-and-cut-and-price for the Cardinality-constrained Multi-cycle Problem in Kidney Exchange

The establishment of kidney exchange programs has dramatically improved rates for kidney transplants by matching donors to compatible patients who would otherwise fail to receive a kidney for transplant. Rather than simply swapping kidneys between two patient-donor pairs, having multiple patient-donors pairs simultaneously donate kidneys in a cyclic manner enables all participants to receive a … Read more

A polyhedral study of the cardinality constrained multi-cycle and multi-chain problem on directed graphs

In this paper, we study the Cardinality Constrained Multi-cycle Problem (CCMcP) and the Car- dinality Constrained Cycle and Chain Problem (CCCCP). A feasible solution allows one or more cardinality-constrained cycles to exist on the digraph. A vertex can only be involved in at most one cycle, and there may be vertices not involved in any … Read more

A unified mixed-integer programming model for simultaneous fluence weight and aperture optimization in VMAT, Tomotherapy, and Cyberknife

In this paper, we propose and study a unified mixed-integer programming model that simultaneously optimizes fluence weights and multi-leaf collimator (MLC) apertures in the treatment planning optimization of VMAT, Tomotherapy, and CyberKnife. The contribution of our model is threefold: i. Our model optimizes the fluence and MLC apertures simultaneously for a given set of control … Read more