inverse planning

Sparsity constrained split feasibility for dose-volume constraints in inverse planning of intensity-modulated photon or proton therapy

  • Mark Brooke
  • Margherita Casiraghi
  • Yair Censor
  • Scott Penfold
  • Reinhard W. Schulte
  • Rafal Zalas
    • Categories Biomedical Applications, Convex Optimization Tags , , , , , ,

    A split feasibility formulation for the inverse problem of intensity-modulated radiation therapy (IMRT) treatment planning with dose-volume constraints (DVCs) included in the planning algorithm is presented. It involves a new type of sparsity constraint that enables the inclusion of a percentage-violation constraint in the model problem and its handling by continuous (as opposed to integer) … Read more

    Controlling the dose distribution with gEUD-type constraints within the convex IMRT optimization framework

  • Tim Craig
  • Harald Keller
  • Michael Sharpe
  • Tamás Terlaky
  • Yuriy Zinchenko
    • Categories Biomedical Applications, Convex Optimization Tags , , , , , ,

    Radiation therapy is an important modality in treating various cancers. Various treatment planning and delivery technologies have emerged to support Intensity Modulated Radiation Therapy (IMRT), creating significant opportunities to advance this type of treatment. We investigate the possibility of including the dose prescription, specified by the DVH, within the convex optimization framework for inverse IMRT … Read more