Subspace accelerated matrix splitting algorithms for bound-constrained quadratic programming and linear complementarity problems

This paper studies the solution of two problems—bound-constrained quadratic programs and linear complementarity problems—by two-phase methods that consist of an active set prediction phase and a subspace phase. The algorithms enjoy favorable convergence properties under weaker assumptions than those assumed for other methods in the literature. The active set prediction phase employs matrix splitting iterations … Read more

A randomized global optimization method for protein-protein docking

In this paper we report results on the problem of docking two large proteins by means of a two-phase monotonic basin hopping method. Given an appropriate force field which is used to measure the interaction energy between two biomolecules which are considered as rigid bodies, we used a randomized global optimization methods based upon the … Read more