Max-min separability: incremental approach and application to supervised data classification

A new algorithm for the computation of a piecewise linear function separating two finite point sets in $n$-dimensional space is developed and the algorithm is applied to solve supervised data classification problems. The algorithm computes hyperplanes incrementally and it finds as many hyperplanes as necessary to separate two sets with respect to some tolerance. An … Read more

Modeling and Simulation of Metabolic Networks for Estimation of Biomass Accumulation Parameters

Metabolic networks are defined as the collection of biochemical reactions within a cell that define the functions of that cell. Due to the growing need to understand the functions of biological organisms for industrial and medical purposes, modeling and simulation of metabolic networks has attracted a lot of attention recently. Traditionally, metabolic networks are modeled … Read more

Derivative Free Optimization Methods for Optimizing Stirrer Configurations

In this paper a numerical approach for the optimization of stirrer configurations is presented. The methodology is based on a flow solver, and a mathematical optimization tool, which are integrated into an automated procedure. The flow solver is based on the discretization of the incompressible Navier-Stokes equations by means of a fully conservative finite-volume method … Read more

Survey of Derivative Free Optimization Methods based on Interpolation

In this survey article we give the basic description of the interpolation based derivative free optimization methods and their variants. We review the recent contributions dealing with the maintaining the geometry of the interpolation set, the management of the trust region radius and the stopping criteria. Derivative free algorithms developed for problems with some structure … Read more

Discrete gradient method: a derivative free method for nonsmooth optimization

In this paper a new derivative-free method is developed for solving unconstrained nonsmooth optimization problems. This method is based on the notion of a discrete gradient. It is demonstrated that the discrete gradients can be used to approximate subgradients of a broad class of nonsmooth functions. It is also shown that the discrete gradients can … Read more