Mark Ruschin

Multistage Stochastic Fractionated Intensity Modulated Radiation Therapy Planning

  • Merve Bodur
  • Mucahit Cevik
  • Andre Augusto Cire
  • Mark Ruschin
  • Juyoung Wang
    • Categories Stochastic Programming Tags , ,

    Intensity modulated radiation therapy (IMRT) is a widely used cancer treatment technique designed to target malignant cells. To enhance its effectiveness on tumors and reduce side effects, radiotherapy plans are usually divided into consecutive treatments, or fractions, that are delivered over multiple weeks. However, typical planning approaches have focused on finding the full sequence of … Read more

    A Multiobjective Approach for Sector Duration Optimization in Stereotactic Radiosurgery Treatment Planning

  • Oylum Şeker
  • Mucahit Cevik
  • Merve Bodur
  • Young Lee-Bartlett
  • Mark Ruschin
    • Categories Biomedical Applications, Multi-Criteria Optimization Tags , , , ,

    Sector duration optimization (SDO) is a problem arising in treatment planning for stereotactic radiosurgery on Gamma Knife. Given a set of isocenter locations, SDO aims to select collimator size configurations and irradiation times thereof such that target tissues receive prescribed doses in a reasonable amount of treatment time, while healthy tissues nearby are spared. We … Read more