Approximate Dynamic Programming for Crowd-shipping with In-store Customers

Crowd-shipping has gained significant attention as a last-mile delivery option over the recent years. In this study, we propose a variant of dynamic crowd-shipping model with in-store customers as crowd-shippers to deliver online orders within few hours. We formulate the problem as a Markov decision process and develop an approximate dynamic programming (ADP) policy using … Read more

Multistage Stochastic Fractionated Intensity Modulated Radiation Therapy Planning

Intensity modulated radiation therapy (IMRT) is a widely used cancer treatment technique designed to target malignant cells. To enhance its effectiveness on tumors and reduce side effects, radiotherapy plans are usually divided into consecutive treatments, or fractions, that are delivered over multiple weeks. However, typical planning approaches have focused on finding the full sequence of … Read more

A Multiobjective Approach for Sector Duration Optimization in Stereotactic Radiosurgery Treatment Planning

Sector duration optimization (SDO) is a problem arising in treatment planning for stereotactic radiosurgery on Gamma Knife. Given a set of isocenter locations, SDO aims to select collimator size configurations and irradiation times thereof such that target tissues receive prescribed doses in a reasonable amount of treatment time, while healthy tissues nearby are spared. We … Read more

On the Impact of Deep Learning-based Time-series Forecasts on Multistage Stochastic Programming Policies

Multistage stochastic programming provides a modeling framework for sequential decision-making problems that involve uncertainty. One typically overlooked aspect of this methodology is how uncertainty is incorporated into modeling. Traditionally, statistical forecasting techniques with simple forms, e.g., (first-order) autoregressive time-series models, are used to extract scenarios to be added to optimization models to represent the uncertain … Read more