Superiorization as a novel strategy for linearly constrained inverse radiotherapy treatment planning

Objective: We apply the superiorization methodology to the intensity-modulated radiation therapy (IMRT) treatment planning problem. In superiorization, linear voxel dose inequality constraints are the fundamental modeling tool within which a feasibility-seeking projection algorithm will seek a feasible point. This algorithm is then perturbed with gradient descent steps to reduce a nonlinear objective function. Approach: Within … Read more

String-Averaging Projected Subgradient Methods for Constrained Minimization

We consider constrained minimization problems and propose to replace the projection onto the entire feasible region, required in the Projected Subgradient Method (PSM), by projections onto the individual sets whose intersection forms the entire feasible region. Specifically, we propose to perform such projections onto the individual sets in an algorithmic regime of a feasibility-seeking iterative … Read more

Convergence and Perturbation Resilience of Dynamic String-Averaging Projection Methods

We consider the convex feasibility problem (CFP) in Hilbert space and concentrate on the study of string-averaging projection (SAP) methods for the CFP, analyzing their convergence and their perturbation resilience. In the past, SAP methods were formulated with a single predetermined set of strings and a single predetermined set of weights. Here we extend the … Read more