We study the problem of computing the tightest upper and lower bounds on the probability that the sum of n dependent Bernoulli random variables exceeds an integer k. Under knowledge of all pairs of bivariate distributions denoted by a complete graph, the bounds are NP-hard to compute. When the bivariate distributions are specified on a … Read more
We propose a new method for the classification task of distinguishing atrial Fibrillation (AFib) from regular atrial tachycardias including atrial Flutter (AFlu) on the basis of a surface electrocardiogram (ECG). Although recently many approaches for an automatic classification of cardiac arrhythmia were proposed, to our knowledge none of them can distinguish between these two. We … Read more
The establishment of kidney exchange programs has dramatically improved rates for kidney transplants by matching donors to compatible patients who would otherwise fail to receive a kidney for transplant. Rather than simply swapping kidneys between two patient-donor pairs, having multiple patient-donors pairs simultaneously donate kidneys in a cyclic manner enables all participants to receive a … Read more
Given an undirected graph, we study the capacitated vertex separator problem which asks to find a subset of vertices of minimum cardinality, the removal of which induces a graph having a bounded number of pairwise disconnected shores (subsets of vertices) of limited cardinality. The problem is of great importance in the analysis and protection of … Read more
The minimum connectivity inference (MCI) problem represents an NP-hard generalization of the well-known minimum spanning tree problem. Given a set of vertices and a finite collection of subsets (of this vertex set), the MCI problem requires to find an edge set of minimal cardinality so that the vertices of each subset are connected. Although the … Read more
The family of Critical Node Detection Problems asks for finding a subset of vertices, deletion of which minimizes or maximizes a predefined connectivity measure on the remaining network. We study a problem of this family called the k-vertex cut problem. The problems asks for determining the minimum weight subset of nodes whose removal disconnects a … Read more
Data are often represented as graphs. Many common tasks in data science are based on distances between entities. While some data science methodologies natively take graphs as their input, there are many more that take their input in vectorial form. In this survey we discuss the fundamental problem of mapping graphs to vectors, and its … Read more
For sparse graphs, the odd cycle polytope can be used to compute useful bounds for the maximum stable set problem quickly. Yannakakis introduced an extended formulation for the odd cycle inequalities of the stable set polytope in 1991, which provides a direct way to optimize over the odd cycle polytope in polynomial time, although there … Read more
Cutting planes from the Boolean Quadric Polytope (BQP) can be used to reduce the optimality gap of the NP-hard nonconvex quadratic program with box constraints (BoxQP). It is known that all cuts of the Chvátal-Gomory closure of the BQP are A-odd cycle inequalities. We obtain a compact extended relaxation of all A-odd cycle inequalities, which … Read more
In state-of-the-art mixed-integer programming solvers, a large array of reduction techniques are applied to simplify the problem and strengthen the model formulation before starting the actual branch-and-cut phase. Despite their mathematical simplicity, these methods can have significant impact on the solvability of a given problem. However, a crucial property for employing presolving techniques successfully is … Read more