Planning of trajectories, i.e. paths over time, is a challenging task. Thereby, the trajectories for involved commodities often have to be considered jointly as separation constraints have to be respected. This is for example the case in robot motion or air traffic management. Involving these discrete separation constraints in the planning of best possible continuous … Read more
Full strong-branching (henceforth referred to as strong-branching) is a well-known variable selection rule that is known experimentally to produce significantly smaller branch-and-bound trees in comparison to all other known variable selection rules. In this paper, we attempt an analysis of the performance of the strong-branching rule both from a theoretical and a computational perspective. On … Read more
In this paper we study the rank of polytopes contained in the 0-1 cube with respect to $t$-branch split cuts and $t$-dimensional lattice cuts for a fixed positive integer $t$. These inequalities are the same as split cuts when $t=1$ and generalize split cuts when $t > 1$. For polytopes contained in the $n$-dimensional 0-1 … Read more
The continuous-time service network design problem (CTSNDP) occurs widely in practice. It aims to minimize the total operational cost by optimizing the schedules of transportation services and the routes of shipments for dispatching, which can occur at any time point along a continuous planning horizon. In order to be cost effective, shipments often wait to … Read more
This paper introduces a computational method for generating metric Travelling Salesperson Problem (TSP) instances having a large integrality gap. The method is based on the solution of an NP-hard problem, called IH-OPT, that takes in input a fractional solution of the Subtour Elimination Problem (SEP) on a TSP instance and compute a TSP instance having … Read more
In this paper, we present a novel scheduling problem, the stem cell culturing problem (SCP), which is identified in an attempt to improve the productivity of a manufacturing system producing a commercialized autologous stem cell therapeutic product for treating an incurable disease. For a given therapeutic product along with the corresponding manufacturing process, which is … Read more
In this work, we consider the integrated problem of locomotive scheduling and driver rostering in rail freight companies. Our aim is to compute an optimal simultaneous assignment of locomotives and drivers to the trains listed in a given order book. Mathematically, this leads to the combination of a set-packing problem with compatibility constraints and a … Read more
Cliques and their generalizations are frequently used to model “tightly knit” clusters in graphs and identifying such clusters is a popular technique used in graph-based data mining. One such model is the $s$-club, which is a vertex subset that induces a subgraph of diameter at most $s$. This model has found use in a variety … Read more
The s-clubs model cohesive social subgroups as vertex subsets that induce subgraphs of diameter at most s. In defender-attacker settings, for low values of s, they can represent tightly-knit communities whose operation is undesirable for the defender. For instance, in online social networks, large communities of malicious accounts can effectively propagate undesirable rumors. In this … Read more
This paper explores new solution approaches for the graph partitioning problem. While the classic formulations for graph partitioning are compact, they either suffer from a poor relaxation, symmetry, or contain a cubic number of constraints regardless of the graph density. These shortcomings often result in poor branch-and-bound performance. We approach this problem from perspective of … Read more