Multi-Stage Robust Mixed-Integer Programming

Multi-stage robust optimization, in which decisions are taken sequentially as new information becomes available about the uncertain problem parameters, is a very versatile yet computationally challenging paradigm for decision-making under uncertainty. In this paper, we propose a new model and solution approach for multi-stage robust mixed-integer programs, which may contain both continuous and discrete decisions … Read more

Column Elimination for Capacitated Vehicle Routing Problems

We introduce a column elimination procedure for the capacitated vehicle routing problem. Our procedure maintains a decision diagram to represent a relaxation of the set of feasible routes, over which we define a constrained network flow. The optimal solution corresponds to a collection of paths in the decision diagram and yields a dual bound. The … Read more

Efficient Discovery of Cost-effective Policies in Sequential, Medical Decision-Making Problems

Cost-effectiveness analysis (CEA) is extensively employed by healthcare policymakers to guide funding decisions and inform optimal design of medical interventions. In the CEA literature, willingness to pay (WTP) serves as a common metric for converting health benefits into monetary value and defining the net monetary benefit of an intervention. However, there is no universally accepted … Read more

The min-Knapsack Problem with Compactness Constraints and Applications in Statistics

In the min-Knapsack problem, one is given a set of items, each having a certain cost and weight. The objective is to select a subset with minimum cost, such that the sum of the weights is not smaller than a given constant. In this paper we introduce an extension of the min-Knapsack problem with additional … Read more

Transportation and Inventory Planning in Serial Supply Chain with Heterogeneous Capacitated Vehicles

We study serial supply chain problems where a product is transported from a supplier to a warehouse (inbound transportation), and then from the warehouse (outbound transportation) to a retailer such that demand for a given planning horizon is satisfied. We consider heterogeneous vehicles of varying capacities for the transportation in each time period, and the … Read more

Decremental State-Space Relaxations for the Basic Traveling Salesman Problem with a Drone

Truck-and-drone routing problems have become an important topic of research in the last decade due to their applications for last-mile deliveries. Despite the large number of publications in this area, the most efficient exact algorithms designed thus far struggle to solve the benchmark instances with 39 or more customers. This fact is true even for … Read more

Data-driven Multistage Distributionally Robust Linear Optimization with Nested Distance

We study multistage distributionally robust linear optimization, where the uncertainty set is defined as a ball of distribution centered at a scenario tree using the nested distance. The resulting minimax problem is notoriously difficult to solve due to its inherent non-convexity. In this paper, we demonstrate that, under mild conditions, the robust risk evaluation of … Read more

A Fast Combinatorial Algorithm for the Bilevel Knapsack Problem with Interdiction Constraints

We consider the bilevel knapsack problem with interdiction constraints, a fundamental bilevel integer programming problem which generalizes the 0-1 knapsack problem. In this problem, there are two knapsacks and \(n\) items. The objective is to select some items to pack into the first knapsack such that the maximum profit attainable from packing some of the … Read more

Compromise Policy for Multi-stage Stochastic Linear Programming: Variance and Bias Reduction

This paper focuses on algorithms for multi-stage stochastic linear programming (MSLP). We propose an ensemble method named the “compromise policy”, which not only reduces the variance of the function approximation but also reduces the bias of the estimated optimal value. It provides a tight lower bound estimate with a confidence interval. By exploiting parallel computing, … Read more

Optimizing Vaccine Distribution in Developing Countries under Natural Disaster Risk

For many developing countries, COVID-19 vaccination roll-out programs are not only slow but vaccination centers are also exposed to the risk of natural disaster, like flooding, which may slow down vaccination progress even further. Policy-makers in developing countries therefore seek to implement strategies that hedge against distribution risk in order for vaccination campaigns to run … Read more