The continuous-time service network design problem (CTSNDP) occurs widely in practice. It aims to minimize the total operational cost by optimizing the schedules of transportation services and the routes of shipments for dispatching, which can occur at any time point along a continuous planning horizon. In order to be cost effective, shipments often wait to … Read more
In this work, we study optimization problems where some cost parameters are not known at decision time and the decision flow is modeled as a two-stage process within a robust optimization setting. We address general problems in which all constraints (including those linking the first and the second stages) are defined by convex functions and … Read more
We study the Sparse Plus Low-Rank decomposition problem (SLR), which is the problem of decomposing a corrupted data matrix into a sparse matrix of perturbations plus a low-rank matrix containing the ground truth. SLR is a fundamental problem in Operations Research and Machine Learning which arises in various applications, including data compression, latent semantic indexing, … Read more
Motivated by applications in cloud computing, we study interval scheduling problems exhibiting economies of scale. An instance is given by a set of jobs, each with start time, end time, and a function representing the cost of scheduling a subset of jobs on the same machine. Specifically, we focus on the max-weight function and non-negative, … Read more
Crowd-shipping has gained significant attention as a last-mile delivery option over the recent years. In this study, we propose a variant of dynamic crowd-shipping model with in-store customers as crowd-shippers to deliver online orders within few hours. We formulate the problem as a Markov decision process and develop an approximate dynamic programming (ADP) policy using … Read more
We introduce EETTlib, an instance library for the Energy-Efficient Train Timetabling problem. The task in this problem is to adjust a given timetable draft such that several key indicators relating to the energy consumption of the resulting railway traffic are minimized. These include peak power consumption, total energy consumption, loss in recuperation energy, fluctuation in … Read more
This paper introduces the multiphase course timetabling problem and presents mathematical formulations and effective solution algorithms to solve it in a real case study. Consider a pool of lessons and a number of students who are required to take a subset of these lessons to graduate. Each lesson consists of a predetermined and consecutive sequence … Read more
this paper, we study the single item capacitated multi-mode lot sizing problem with periodic carbon emission constraints where the carbon emission constraints define an upper bound for the average emission per product produced in any period. The uncapacitated version of this problem was introduced in Absi et al. (2013) and solved in polynomial time. We … Read more
The uncertainty in infusion durations and non-homogeneous care level needs of patients are the critical factors that lead to difficulties in chemotherapy scheduling. We study the problem of scheduling patient appointments and assigning patients to nurses under uncertainty in infusion durations for a given day. We consider instantaneous nurse workload, represented in terms of total … Read more
In this paper, we present a novel scheduling problem, the stem cell culturing problem (SCP), which is identified in an attempt to improve the productivity of a manufacturing system producing a commercialized autologous stem cell therapeutic product for treating an incurable disease. For a given therapeutic product along with the corresponding manufacturing process, which is … Read more