We study a class of quadratic stochastic programs where the distribution of random variables has unknown parameters. A traditional approach is to estimate the parameters using a maximum likelihood estimator (MLE) and to use this as input in the optimization problem. For the unconstrained case, we show that an estimator that “shrinks” the MLE towards … Read more
This paper addresses the manufacturing and distribution of short-lived radio-pharmaceuticals which are mainly used in diagnostic imaging studies. We develop a mixed integer nonlinear optimization model that is flexible enough to capture the complex underlying nuclear physics of the production process of fludeoxyglucose (FDG), which is widely used in oncology and cardiology, as well as … Read more
This paper deals with the modeling of power flow in a transmission grid within the multi-sectoral multi-energy long-term regional energy model ETEM-SG. This extension of the model allows a better representation of demand response for flexible loads triggered by nodal marginal cost pricing. To keep the global model in the realm of linear program- ming … Read more
NeatWork is an advanced optimization and simulation tool for the design of purely gravity-driven water distribution systems aiming at delivering clean water to poor rural communities. The exclusion of any adjustable devices, such as pumps and valves, for controlling pressures and flows is motivated by two main reasons: firstly, the system should be as simple … Read more
The effect of preconditioning linear weighted least-squares using an approximation of the model matrix is analyzed, showing the interplay of the eigenstructures of both the model and weighting matrices. A small example is given illustrating the resulting potential inefficiency of such preconditioners. Consequences of these results in the context of the weakly-constrained 4D-Var data assimilation … Read more
This paper discusses the practical use of the saddle variational formulation for the weakly-constrained 4D-VAR method in data assimilation. It is shown that the method, in its original form, may produce erratic results or diverge because of the inherent lack of monotonicity of the produced objective function values. Convergent, variationaly coherent variants of the algorithm … Read more
The bootstrap is a nonparametric approach for calculating quantities, such as confidence intervals, directly from data. Since calculating exact bootstrap quantities is believed to be intractable, randomized resampling algorithms are traditionally used. Motivated by the fact that the variability from randomization can lead to inaccurate outputs, we propose a deterministic approach. First, we establish several … Read more
We consider nonlinear and nonsmooth mixing aspects in gas transport optimization problems. As mixed-integer reformulations of pooling-type mixing models already render small-size instances computationally intractable, we investigate the applicability of smooth nonlinear programming techniques for equivalent complementarity-based reformulations. Based on recent results for remodeling piecewise affine constraints using an inverse parametric quadratic programming approach, we … Read more
Testing a given matrix for membership in the family of Bernoulli matrices is a longstanding problem, the many applications of Bernoulli vectors in computer science, finance, medicine, and operations research emphasize its practical relevance. A novel approach towards this problem was taken by [Fiebig et al., 2017] for lowdimensional settings d
Nonconvex penalty methods for sparse modeling in linear regression have been a topic of fervent interest in recent years. Herein, we study a family of nonconvex penalty functions that we call the trimmed Lasso and that offers exact control over the desired level of sparsity of estimators. We analyze its structural properties and in doing … Read more