Developments in mathematical algorithms and computational tools for proton CT and particle therapy treatment planning

We summarize recent results and ongoing activities in mathematical algorithms and computer science methods related to proton computed tomography (pCT) and intensitymodulated particle therapy (IMPT) treatment planning. Proton therapy necessitates a high level of delivery accuracy to exploit the selective targeting imparted by the Bragg peak. For this purpose, pCT utilizes the proton beam itself … Read more

Decision Intelligence for Nationwide Ventilator Allocation

Many states in the U.S. have faced shortages of medical resources because of the surge in the number of patients suffering from COVID-19. As many projections indicate, the situation will be far worse in coming months. The upcoming challenge is not only due to the exponential growth in cases but also because of inherent uncertainty … Read more

Finding the strongest stable massless column with a follower load and relocatable concentrated masses

We consider the problem of optimal placement of concentrated masses along a massless elastic column that is clamped at one end and loaded by a nonconservative follower force at the free end. The goal is to find the largest possible interval such that the variation in the loading parameter within this interval preserves stability of … Read more

Calmness of a perturbed Cournot Oligopoly Game with nonsmooth cost functions

This article deals with the calmness of a solution map of a Cournot Oligopoly Game with nonsmooth cost functions. The fact that the cost functions are not supposed to be differentiable allows for considering cases where some firms have diferent units of production, which have diferent marginal costs. In order to obtain results about the … Read more

A Class of Smooth Exact Penalty Function Methods for Optimization Problems with Orthogonality Constraints

Updating the augmented Lagrangian multiplier by closed-form expression yields efficient first-order infeasible approach for optimization problems with orthogonality constraints. Hence, parallelization becomes tractable in solving this type of problems. Inspired by this closed-form updating scheme, we propose an exact penalty function model with compact convex constraints (PenC). We show that PenC can act as an … Read more

An algorithm for optimization with disjoint linear constraints and its application for predicting rain

A specialized algorithm for quadratic optimization (QO, or, formerly, QP) with disjoint linear constraints is presented. In the considered class of problems, a subset of variables are subject to linear equality constraints, while variables in a different subset are constrained to remain in a convex set. The proposed algorithm exploits the structure by combining steps … Read more

Derivative-Free Superiorization: Principle and Algorithm

The superiorization methodology is intended to work with input data of constrained minimization problems, that is, a target function and a set of constraints. However, it is based on an antipodal way of thinking to what leads to constrained minimization methods. Instead of adapting unconstrained minimization algorithms to handling constraints, it adapts feasibility-seeking algorithms to … Read more

A Survey of Recent Scalability Improvements for Semidefinite Programming with Applications in Machine Learning, Control, and Robotics

Historically, scalability has been a major challenge to the successful application of semidefinite programming in fields such as machine learning, control, and robotics. In this paper, we survey recent approaches for addressing this challenge including (i) approaches for exploiting structure (e.g., sparsity and symmetry) in a problem, (ii) approaches that produce low-rank approximate solutions to … Read more

Basis Pursuit Denoise with Nonsmooth Constraints

Level-set optimization formulations with data-driven constraints minimize a regularization functional subject to matching observations to a given error level. These formulations are widely used, particularly for matrix completion and sparsity promotion in data interpolation and denoising. The misfit level is typically measured in the l2 norm, or other smooth metrics. In this paper, we present … Read more

Time-Varying Semidefinite Programs

We study time-varying semidefinite programs (TV-SDPs), which are semidefinite programs whose data (and solutions) are functions of time. Our focus is on the setting where the data varies polynomially with time. We show that under a strict feasibility assumption, restricting the solutions to also be polynomial functions of time does not change the optimal value … Read more