We study robust versions of the uncapacitated lot sizing problem, where the demand is subject to uncertainty. The robust models are guided by three parameters, namely, the total scaled uncertainty budget, the minimum number of periods in which one would like the demand to be protected against uncertainty, and the minimum scaled protection level per … Read more
Mathematical modeling of market design issues in liberalized electricity markets often leads to mixed-integer nonlinear multilevel optimization problems for which no general-purpose solvers exist and which are intractable in general. In this work, we consider the problem of splitting a market area into a given number of price zones such that the resulting market design … Read more
This paper introduces the Selective Traveling Salesman Problem with Draught Limits, an extension of Traveling Salesman Problem with Draught Limits, wherein the goal is to design maximal profit tour respecting draught limit constraints of the visited ports. We propose a mixed integer linear programming formulation for this problem. The proposed mixed integer program is used … Read more
It is widely recognized that early diagnosis of most types of cancers can increase the chances of full recovery or substantially prolong the life of patients. Positron Emission Tomography (PET) has become the standard way to diagnose many types of cancers by generating high quality images of the affected organs. In order to create an … Read more
This paper presents an extensive computational study of simple, but prominent matheuristics (i.e., heuristics that rely on mathematical programming models) to fi nd high quality ship schedules and inventory policies for a class of maritime inventory routing problems. Our computational experiments are performed on a set of the publicly available MIRPLib instances. This class of inventory … Read more
In this paper we present two mixed-integer programming formulations for the curriculum based course timetabling problem (CTT). We show that the formulations contain underlying network structures by dividing the CTT into two separate models and then connect the two models using flow formulation techniques. The first mixed-integer programming formulation is based on an underlying minimum … Read more
We formulate an integer program to solve a highly constrained academic timetabling problem at the United States Merchant Marine Academy. The IP instance that results from our real case study has approximately both 170,000 rows and columns and solves to near optimality in 12 hours, using a commercial solver. Our model is applicable to both … Read more
The university course timetabling problem deals with the task of scheduling lectures of a set of university courses into a given number of rooms and time periods, taking into account various hard and soft constraints. The goal of the International Timetabling Competitions ITC2002 and ITC2007 was to establish models for comparison that cover the most … Read more
We investigate a robust approach for solving the Capacitated Vehicle Routing Problem (CVRP) with uncertain travel times. It is based on the concept of K-adaptability, which allows to calculate a set of k feasible solutions in a preprocessing phase before the scenario is revealed. Once a scenario occurs, the corresponding best solution may be picked … Read more
Radiation therapy is considered to be one of important treatment protocols for cancers. Radiation therapy employs several beams of ionizing radiation to kill cancer tumors, but such irradiation also causes damage to normal tissues. Therefore, a treatment plan should satisfy dose-volume constraints (DVCs). Intensity-modulated radiotherapy treatment (IMRT) enables to control the beam intensities and gives … Read more