We consider a variant of the vehicle routing problems with time windows, where the objective includes the inconvenience cost modeled by a convex function on each node. We formulate this mixed integer convex program using a novel set partitioning formulation, by considering all combinations of routes and block structures over the routes. We apply a … Read more
Bioattacks, i.e., the intentional release of pathogens or biotoxins against humans to cause serious illness and death, pose a significant threat to public health and safety due to the availability of pathogens worldwide, scale of impact, and short treatment time window. In this paper, we focus on the problem of prepositioning inventory of medical countermeasures … Read more
We introduce the Stochastic multistage fixed charge transportation problem in which a producer has to ship an uncertain load to a customer within a deadline. At each time period, a fixed transportation price can be paid to buy a transportation capacity. If the transportation capacity is used, the supplier also pays an uncertain unit transportation … Read more
We present a two-stage stochastic linear programming model to manage the inventory of vaccine vials in developing countries. In these countries immunization programs often involve targeted outreach services in remote locations. Organizations managing these programs are in need of tools which identify inventory replenishment and vaccine utilization plans to minimize costs and wastage while achieving … Read more
This paper studies the emergency service facility location problem in an uncertain environment. The main focus is the integration of uncertainty regarding the covered area due to uncertain traveling times. Previous approaches only consider either probabilistic or fuzzy optimization to cope with uncertainty. However, in many real-world problems the required statistical parameters are not precisely … Read more
In this paper we study integer linear programming models and develop branch-and-cut algorithms to solve the Black-and-White Traveling Salesman Problem (BWTSP) (Bourgeois et al., 2003) which is a variant of the well known Traveling Salesman Problem (TSP). Two strategies to model the BWTSP have been used in the literature. The problem is either modeled on … Read more
With increasing penetration of renewable energy into the power grid and its intermittent nature, it is crucial and challenging for system operators to provide reliable and cost effective daily electricity generation scheduling. In this dissertation, we present our recently developed innovative modeling and solution approaches to address this challenging problem. We start with developing several … Read more
We study the one-warehouse multi-retailer (OWMR) problem under deterministic dynamic demand and concave batch order costs, where order batches have an identical capacity and the order cost function for each facility is concave within the batch. Under appropriate assumptions on holding cost structure, we obtain lower bounds via a decomposition that splits the two-echelon problem … Read more
The incomplete hub location problem with and without hop-constraints is modeled using a Leontief substitution system approach. The Leontief formalism provides a set of important theoretical properties and delivers formulations with tight linear bounds that can explicitly incorporate hop constraints for each origin-destination pair of demands. Furthermore, the proposed formulations are amenable to a Benders … Read more
A non-linear lifting procedure is proposed to generate high density Benders cuts. The new denser cuts cover more master problem variables than traditional Benders cuts, shortening the required number of iterations to reach optimality, and speeding up the Benders decomposition algorithm. To lessen the intricacy stemmed from the non-linearity, a simple outer approximation lineariza- tion … Read more