Recent Progress Using Matheuristics for Strategic Maritime Inventory Routing

This paper presents an extensive computational study of simple, but prominent matheuristics (i.e., heuristics that rely on mathematical programming models) to fi nd high quality ship schedules and inventory policies for a class of maritime inventory routing problems. Our computational experiments are performed on a set of the publicly available MIRPLib instances. This class of inventory … Read more

An optimization-based approach for delivering radio-pharmaceuticals to medical imaging centers

It is widely recognized that early diagnosis of most types of cancers can increase the chances of full recovery or substantially prolong the life of patients. Positron Emission Tomography (PET) has become the standard way to diagnose many types of cancers by generating high quality images of the affected organs. In order to create an … Read more

Flow formulations for curriculum-based course timetabling

In this paper we present two mixed-integer programming formulations for the curriculum based course timetabling problem (CTT). We show that the formulations contain underlying network structures by dividing the CTT into two separate models and then connect the two models using flow formulation techniques. The first mixed-integer programming formulation is based on an underlying minimum … Read more

Automated timetabling for small colleges and high schools using huge integer programs

We formulate an integer program to solve a highly constrained academic timetabling problem at the United States Merchant Marine Academy. The IP instance that results from our real case study has approximately both 170,000 rows and columns and solves to near optimality in 12 hours, using a commercial solver. Our model is applicable to both … Read more

New Constraints and Features for the University Course Timetabling Problem

The university course timetabling problem deals with the task of scheduling lectures of a set of university courses into a given number of rooms and time periods, taking into account various hard and soft constraints. The goal of the International Timetabling Competitions ITC2002 and ITC2007 was to establish models for comparison that cover the most … Read more

A Robust Approach to the Capacitated Vehicle Routing Problem with Uncertain Costs

We investigate a robust approach for solving the Capacitated Vehicle Routing Problem (CVRP) with uncertain travel times. It is based on the concept of K-adaptability, which allows to calculate a set of k feasible solutions in a preprocessing phase before the scenario is revealed. Once a scenario occurs, the corresponding best solution may be picked … Read more

A Successive LP Approach with C-VaR Type Constraints for IMRT Optimization

Radiation therapy is considered to be one of important treatment protocols for cancers. Radiation therapy employs several beams of ionizing radiation to kill cancer tumors, but such irradiation also causes damage to normal tissues. Therefore, a treatment plan should satisfy dose-volume constraints (DVCs). Intensity-modulated radiotherapy treatment (IMRT) enables to control the beam intensities and gives … Read more

Risk management for forestry planning under uncertainty in demand and prices.

The forest-harvesting and road-construction planning problem basically consists of managing land designated for timber production and divided into harvest cells. For each time period in the given time horizon one must decide which cells to cut and what access roads to build in order to maximize expected net profit under a risk manageable scheme to … Read more

A Distance-Limited Continuous Location-Allocation Problem for Spatial Planning of Decentralized Systems

We introduce a new continuous location-allocation problem where the facilities have both a xed opening cost and a coverage distance limitation. The problem might have wide applications especially in the spatial planning of water and/or energy access networks where the coverage distance might be associated with the physical loss constraints. We formulate a mixed integer … Read more

The Min-up/Min-down Unit Commitment polytope

The Min-up/min-down Unit Commitment Problem (MUCP) is to find a minimum-cost production plan on a discrete time horizon for a set of fossil-fuel units for electricity production. At each time period, the total production has to meet a forecasted demand. Each unit must satisfy minimum up-time and down-time constraints besides featuring production and start-up costs. … Read more