The tourist trip design problem is an extension of the orienteering problem applied to tourism. The problem consists in selecting a subset of locations to visit from among a larger set while maximizing the benefit for the tourist. The benefit is given by the sum of the rewards collected at each location visited. We consider … Read more
This paper addresses a real-life personnel scheduling problem in the context of Covid-19 pandemic, arising in a large Italian pharmaceutical distribution warehouse. In this case study, the challenge is to determine a schedule that attempts to meet the contractual working time of the employees, considering the fact that they must be divided into mutually exclusive … Read more
Over the last few decades, the Airline Scheduling Process (ASP) has received an unprecedented attention from airliners and operations research society. Conventionally, the Airline Scheduling Process is decomposed into four sub-problems namely-Schedule Generation, Fleet Assignment, aircraft Routing, and Crew Scheduling which are solved sequentially in order to incorporate tractability and feasibility in the overall process. … Read more
The R&D management in any major research pharmaceutical company is constantly faced with the need to make complicated activity scheduling and resource allocation decisions, as they carry out scientific work to develop new therapeutic products. This paper describes how we develop a decision support tool that allows practitioners to determine portfolio-wide optimal schedules in a … Read more
In this paper, we study the decision process of assigning elective surgery patients to available surgical blocks in multiple operating rooms (OR) under random surgery durations, random postoperative length-of-stay in the intensive care unit (ICU), and limited capacity of ICU. The probability distributions of random parameters are assumed to be ambiguous, and only the mean … Read more
In this paper, we study the problem of planning the growth of crops on shelves in vertical farming cabinets under controlled growth conditions. By adjusting temperature, humidity, light, and other environmental conditions in different parts of the cabinets, a planner must ensure that crop growth is able to satisfy some deterministic demand. We prove this … Read more
The thermal unit commitment (UC) problem often can be formulated as a mixed integer quadratic programming (MIQP), which is difficult to solve efficiently, especially for large-scale instances. The tighter characteristic re-duces the search space, therefore, as a natural conse-quence, significantly reduces the computational burden. In the literature, many tightened formulations for single units with parts … Read more
Mine planning optimization aims at maximizing the profit obtained from extracting valuable ore. Beyond its theoretical complexity (the open-pit mining problem with capacity constraints reduces to a knapsack problem with precedence constraints, which is NP-hard), practical instances of the problem usually involve a large to very large number of decision variables, typically of the order … Read more
Timetabling of railway traffic and other modes of transport is among the most prominent applications of discrete optimization in practice. However, it has only been recently that the connection between timetabling and energy consumption has been studied more extensively. In our joint project VAG Verkehrs-Aktiengesellschaft, the transit authority and operator of underground transport in the … Read more
Healthcare facilities are struggling in fighting the spread of COVID-19. While machines needed for patients such as ventilators can be built or bought, healthcare personnel is a very scarce resource that cannot be increased by hospitals in a short period. Furthermore, healthcare personnel is getting sick while taking care of infected people, increasing this shortage … Read more