We propose a novel, ecient approach for obtaining high-quality experimental designs for event-related functional magnetic resonance imaging (ER-fMRI). Our approach combines a greedy hillclimbing algorithm and a cyclic permutation method. When searching for optimal ER-fMRI designs, the proposed approach focuses only on a promising restricted class of designs with equal frequency of occurrence across stimulus … Read more
In this paper we propose an extension of the proximal point method to solve minimization problems with quasiconvex locally Lipschitz objective functions on Hadamard manifolds. To reach this goal, we use the concept of Clarke subdifferential on Hadamard manifolds and assuming that the function is bounded from below, we prove the global convergence of the … Read more
This paper proposes a new probabilistic algorithm for solving multi-objective optimization problems – Probability-Driven Search Algorithm. The algorithm uses probabilities to control the process in search of Pareto optimal solutions. Especially, we use the absorbing Markov Chain to argue the convergence of the algorithm. We test this approach by implementing the algorithm on some benchmark … Read more
Bi-level problems are optimisation problems in which some of the decision variables must optimise a subordinate (lower-level) problem. In general, the lower-level problem can possess multiple optimal solutions. One therefore distinguishes between optimistic formulations, which assume that the most favourable lower-level solution is implemented, and pessimistic formulations, in which the most adverse lower-level solution is … Read more
Mathematical programming problems involving nonconvexities are usually solved to optimality using a (spatial) Branch-and-Bound algorithm. Algorithmic efficiency depends on many factors, among which the widths of the bounding box for the problem variables at each Branch-and-Bound node naturally plays a critical role. The practically fastest box-tightening algorithm is known as FBBT (Feasibility-Based Bounds Tightening): an … Read more
Estimating parameters from data is a key stage of the modelling process, particularly in biological systems where many parameters need to be estimated from sparse and noisy data sets. Over the years, a variety of heuristics have been proposed to solve this complex optimisation problem, with good results in some cases yet with limitations in … Read more
We present an extension of the proximal point method with Bregman distances to solve Variational Inequality Problems (VIP) on Hadamard manifolds (simply connected finite dimensional Riemannian manifold with nonpositive sectional curvature). Under some natural assumption, as for example, the existence of solutions of the (VIP) and the monotonicity of the multivalued vector field, we prove … Read more
In this paper we derive strong linear inequalities for sets of the form {(x, q) ∈ R^d × R : q ≥ Q(x), x ∈ R^d − int(P ) }, where Q(x) : R^d → R is a quadratic function, P ⊂ R^d and “int” denotes interior. Of particular but not exclusive interest is the … Read more
We present a branch and bound algorithm for the global optimization of a twice differentiable nonconvex objective function with a Lipschitz continuous Hessian over a compact, convex set. The algorithm is based on applying cubic regularisation techniques to the objective function within an overlapping branch and bound algorithm for convex constrained global optimization. Unlike other … Read more
The multilinear least-squares (MLLS) problem is an extension of the linear least-squares problem. The difference is that a multilinear operator is used in place of a matrix-vector product. The MLLS is typically a large-scale problem characterized by a large number of local minimizers. It originates, for instance, from the design of filter networks. We present … Read more