Second-order cone programming problems are a tractable subclass of convex optimization problems and there are known polynomial algorithms for solving them. Stochastic second-order cone programming problems have also been studied in the past decade and efficient algorithms for solving them exist. A new class of interest to optimization community and practitioners is the mixed-integer version … Read more
We investigate the problem of recovering a partially observed high-rank matrix whose columns obey a nonlinear structure such as a union of subspaces, an algebraic variety or grouped in clusters. The recovery problem is formulated as the rank minimization of a nonlinear feature map applied to the original matrix, which is then further approximated by … Read more
The pandemic caused by the corona virus SARS-CoV-2 raised many new challenges for humanity. For instance, governments imposed regulations such as lockdowns, resulting in supply chain shocks at different tiers. Additionally, delivery services reached their capacity limits because the demand for mail orders soared temporarily during the lockdowns. We argue that one option to support … Read more
This work presents a general method for linearizing bilinear terms in the upper level of bilevel optimization problems when the bilinear terms are products of the primal and dual variables of the lower level. Bilinear terms of this form often appear in energy market optimization models where the dual variable represents the market price of … Read more
We summarize recent results and ongoing activities in mathematical algorithms and computer science methods related to proton computed tomography (pCT) and intensitymodulated particle therapy (IMPT) treatment planning. Proton therapy necessitates a high level of delivery accuracy to exploit the selective targeting imparted by the Bragg peak. For this purpose, pCT utilizes the proton beam itself … Read more
Generation Capacity Expansion Planning (GCEP) requires high temporal resolution to account for the volatility of renewable energy supply. Because the GCEP optimization problem is often computationally intractable, time-series input data are often aggregated to representative periods using clustering. However, clustering removes extreme events, which are important to achieve reliable system designs. We present a method … Read more
Cut-generating linear programs (CGLPs) play a key role as a separation oracle to produce valid inequalities for the feasible region of mixed-integer programs. When incorporated inside branch-and-bound, the cutting planes obtained from CGLPs help to tighten relaxations and improve dual bounds. However, running the CGLPs at the nodes of the branch-and-bound tree is computationally cumbersome … Read more
Problem definition: Effective hypertension management is critical to reducing consequences of atherosclerotic cardiovascular disease, a leading cause of death in the United States. Clinical guidelines for hypertension can be enhanced using decision-analytic approaches, capable of capturing many complexities in treatment planning. However, model-generated recommendations may be uninterpretable/unintuitive, limiting their acceptability in practice. We address this … Read more
Many states in the U.S. have faced shortages of medical resources because of the surge in the number of patients suffering from COVID-19. As many projections indicate, the situation will be far worse in coming months. The upcoming challenge is not only due to the exponential growth in cases but also because of inherent uncertainty … Read more
Motivated by issues dealing with delivery of emergency medical products during humanitarian disasters, this paper addresses the general problem of delivering perishable items to remote demands accessible only by helicopters or drones. Each drone operates out of platforms that may be moved when not in use and each drone has a limited delivery range to … Read more