Convex Optimization Methods for Dimension Reduction and Coefficient Estimation in Multivariate Linear Regression

In this paper, we study convex optimization methods for computing the trace norm regularized least squares estimate in multivariate linear regression. The so-called factor estimation and selection (FES) method, recently proposed by Yuan et al. [17], conducts parameter estimation and factor selection simultaneously and have been shown to enjoy nice properties in both large and … Read more

An Adaptive Linear Approximation Algorithm for Copositive Programs

We study linear optimization problems over the cone of copositive matrices. These problems appear in nonconvex quadratic and binary optimization, for instance the maximum clique problem and other combinatorial problems can be reformulated as such a problem. We present new polyhedral inner and outer approximations of the copositive cone which we show to be exact … Read more

A Class Representative Model for Pure Parsimony Haplotyping

Parsimonious haplotype estimation from aligned Single Nucleotide Polymorphism (SNP) fragments consists of finding the minimum number of haplotypes necessary to explain a given set of genotypes. This problem is known to be NP-Hard. Here we describe a new integer linear-programming model to tackle this problem based on the concept of class representatives, already used for … Read more

Size constrained graph partitioning polytope. Part I: Dimension and trivial facets

We consider the problem of clustering a set of items into subsets whose sizes are bounded from above and below. We formulate the problem as a graph partitioning problem and propose an integer programming model for solving it. This formulation generalizes several well-known graph partitioning problems from the literature like the clique partitioning problem, the … Read more

Size constrained graph partitioning polytope. Part II: Non-trivial facets

We consider the problem of clustering a set of items into subsets whose sizes are bounded from above and below. We formulate the problem as a graph partitioning problem and propose an integer programming model for solving it. This formulation generalizes several well-known graph partitioning problems from the literature like the clique partitioning problem, the … Read more

LASSO-Patternsearch Algorithm with Application to Ophthalmology and Genomic Data

The LASSO-Patternsearch algorithm is proposed as a two-step method to identify clusters or patterns of multiple risk factors for outcomes of interest in demographic and genomic studies. The predictor variables are dichotomous or can be coded as dichotomous. Many diseases are suspected of having multiple interacting risk factors acting in concert, and it is of … Read more

A Redundant Klee-Minty Construction with All the Redundant Constraints Touching the Feasible Region

By introducing some redundant Klee-Minty constructions, we have previously shown that the central path may visit every vertex of the Klee-Minty cube having $2^n-2$ “sharp” turns in dimension $n$. In all of the previous constructions, the maximum of the distances of the redundant constraints to the corresponding facets is an exponential number of the dimension … Read more

Formulation and solution strategies for nonparametric nonlinear stochastic programs, with an application in finance

We consider a class of stochastic programming models where the uncertainty is classically represented using parametric distributions families. The parameters are then usually estimated together with the optimal value of the problem. However, misspecification of the underlying random variables often leads to irrealistic results when little is known about their true distributions. We propose to … Read more

A difference of convex formulation of value-at-risk constrained optimization

In this article, we present a representation of value-at-risk (VaR) as a difference of convex (D.C.) functions in the case where the distribution of the underlying random variable is discrete and has finitely many atoms. The D.C. representation is used to study a financial risk-return portfolio selection problem with a VaR constraint. A branch-and-bound algorithm … Read more