Abstract—In this paper, we present a method to solve inverse problems of electromagnetic circuit design which are formulated as a topology optimization problem. Indeed, by imposing the magnetic field inside a region, we search a best material distribution into variable domains. In order to perform this, we minimize the quadratic error between the prescribed magnetic … Read more
We are interested in optimizing the co-administration of two drugs for some acute myeloid leukemias (AML), and we are looking for in vitro protocols as a first step. This issue can be formulated as an optimal control problem. The dynamics of leukemic cell populations in culture is given by age-structured partial differential equations, which can … Read more
It is often the case that the computed optimal solution of an optimization problem cannot be implemented directly, irrespective of data accuracy, due to either (i) technological limitations (such as physical tolerances of machines or processes), (ii) the deliberate simplification of a model to keep it tractable (by ignoring certain types of constraints that pose … Read more
We propose to use a decomposition of large-scale incremental four dimensional (4D-Var) data assimilation problems in order to make their numerical solution more efficient. This decomposition is based on exploiting an adaptive hierarchy of the observations. Starting with a low-cardinality set and the solution of its corresponding optimization problem, observations are adaptively added based on … Read more
This paper provides a theoretical and experimental comparison between conjugate-gradients and multigrid, two iterative schemes for solving linear systems, in the context of applying diffusion-based correlation models in data assimilation. In this context, a large number of such systems has to be (approximately) solved if the implicit mode is chosen for integrating the involved diffusion … Read more
This paper introduces a new method for proving global stability of fluid flows through the construction of Lyapunov functionals. For finite dimensional approximations of fluid systems, we show how one can exploit recently developed optimization methods based on sum-of-squares decomposition to construct a polynomial Lyapunov function. We then show how these methods can be extended … Read more
When solving nonlinear least-squares problems, it is often useful to regularize the problem using a quadratic term, a practice which is especially common in applications arising in inverse calculations. A solution method derived from a trust-region Gauss-Newton algorithm is analyzed for such applications, where, contrary to the standard algorithm, the least-squares subproblem solved at each … Read more
Many physical phenomena, governed by partial differential equations (PDEs), are second order in nature. This makes sense to pose the control on the second order derivatives of the field solution, in addition to zero and first order ones, to consistently control the underlaying process. However, this type of control is nontrivial and to the best … Read more
We develop and investigate two preconditioners for a basic linear iterative splitting method for the numerical solution of linear-quadratic optimization problems with time-periodic parabolic PDE constraints. The resulting real-valued linear system to be solved is symmetric indefinite. We propose all-at-once symmetric indefinite preconditioners based on a Newton–Picard approach which divides the variable space into slow … Read more
The properties of multilevel optimization problems defined on a hierarchy of discretization grids can be used to define approximate secant equations, which describe the second-order behaviour of the objective function. Following earlier work by Gratton and Toint (2009), we introduce a quasi-Newton method (with a linesearch) and a nonlinear conjugate gradient method that both take … Read more