Anesthesiologist Scheduling with Handoffs: A Combined Approach of Optimization and Human Factors

We present a two-stage stochastic programming model for optimizing anesthesiologist schedules, explicitly accounting for uncertainty in surgery durations and anesthesiologist handoffs. To inform model design, we conducted an online survey at our partner institution to identify key factors affecting the quality of intraoperative anesthesiologist handoffs. Insights from the survey results are incorporated into the model, … Read more

Optimal personnel scheduling in hospital pharmacies considering management and operators priorities

In this paper, we address the problem of allocating and scheduling employees for work shifts in the pharmacy sector of a private hospital. To tackle this issue, we introduce the pharmacy staff scheduling problem (PSSP) in the literature. To solve the problem, we propose a mixed-integer programming formulation that considers various aspects, such as the … Read more

A Randomized Algorithm for Sparse PCA based on the Basic SDP Relaxation

Sparse Principal Component Analysis (SPCA) is a fundamental technique for dimensionality reduction, and is NP-hard. In this paper, we introduce a randomized approximation algorithm for SPCA, which is based on the basic SDP relaxation. Our algorithm has an approximation ratio of at most the sparsity constant with high probability, if called enough times. Under a … Read more

Implied Integrality in Mixed-Integer Optimization

Implied-integer detection is a well-known presolving technique that is used by many Mixed-Integer Linear Programming solvers. Informally, a variable is said to be implied integer if its integrality is enforced implicitly by integrality of other variables and the constraints of a problem. In this work we formalize the definition of implied integrality by taking a … Read more

Strength of the Upper Bounds for the Edge-Weighted Maximum Clique Problem

We theoretically and computationally compare the strength of the two main upper bounds from the literature on the optimal value of the Edge-Weighted Maximum Clique Problem (EWMCP). We provide a set of instances for which the ratio between either of the two upper bounds and the optimal value of the EWMCP is unbounded. This result … Read more

Random-Restart Best-Response Dynamics for Large-Scale Integer Programming Games and Their Applications

This paper presents scalable algorithms for computing pure Nash equilibria (PNEs) in large-scale integer programming games (IPGs), where existing exact methods typically handle only small numbers of players. Motivated by a county-level aquatic invasive species (AIS) prevention problem with 84 decision makers, we develop and analyze random-restart best-response dynamics (RR-BRD), a randomized search framework for … Read more

A Dantzig-Wolfe Single-Level Reformulation for Mixed-Integer Linear Bilevel Optimization: Exact and Heuristic Approaches

Bilevel optimization problems arise in numerous real-world applications. While single-level reformulations are a common strategy for solving convex bilevel problems, such approaches usually fail when the follower’s problem includes integer variables. In this paper, we present the first single-level reformulation for mixed-integer linear bilevel optimization, which does not rely on the follower’s value function. Our … Read more

A relax-fix-and-exclude algorithm for an MINLP problem with multilinear interpolations

This paper introduces a novel algorithm for Mixed-Integer Nonlinear Programming (MINLP) problems with multilinear interpolations of look-up tables. These problems arise when objectives or constraints contain black-box functions only known at a finite set of evaluations on a predefined grid. We derive a piecewise-linear relaxation for the multilinear interpolants, which require an MINLP formulation. Supported … Read more

Two-way Cutting-plane Algorithm for Best Subset Selection Considering Multicollinearity

When linear dependence exists between some explanatory variables in a regression model, the estimates of regression coefficients become unstable, thereby making the interpretation of the estimation results unreliable. To eliminate such multicollinearity, we propose a high-performance method for selecting the best subset of explanatory variables for linear and logistic regression models. Specifically, we first derive … Read more

Branch-and-Cut for Mixed-Integer Nash Equilibrium Problems

We consider Nash equilibrium problems with mixed-integer variables in which each player solves a mixed-integer optimization problem parameterized in the rivals’ strategies. We distinguish between standard Nash equilibrium problems (NEP), where the parameterization acts only on the players’ cost functions and generalized Nash equilibrium problems (GNEPs), where, additionally, the strategy spaces of the players may … Read more