This paper addresses the manufacturing and distribution of short-lived radio-pharmaceuticals which are mainly used in diagnostic imaging studies. We develop a mixed integer nonlinear optimization model that is flexible enough to capture the complex underlying nuclear physics of the production process of fludeoxyglucose (FDG), which is widely used in oncology and cardiology, as well as … Read more
We consider uniqueness and multiplicity of market equilibria in a short-run setup where traded quantities of electricity are transported through a capacitated network in which power flows have to satisfy the classical lossless DC approximation. The firms face fluctuating demand and decide on their production, which is constrained by given capacities. Today, uniqueness of such … Read more
NeatWork is an advanced optimization and simulation tool for the design of purely gravity-driven water distribution systems aiming at delivering clean water to poor rural communities. The exclusion of any adjustable devices, such as pumps and valves, for controlling pressures and flows is motivated by two main reasons: firstly, the system should be as simple … Read more
This paper deals with the modeling of power flow in a transmission grid within the multi-sectoral multi-energy long-term regional energy model ETEM-SG. This extension of the model allows a better representation of demand response for flexible loads triggered by nodal marginal cost pricing. To keep the global model in the realm of linear program- ming … Read more
In this paper, we investigate optimal policies of distributionally robust (risk averse) inventory models. We demonstrate that if the respective risk measures are not strictly monotone, then there may exist infinitely many optimal policies which are not base-stock and not time consistent. This is in a sharp contrast with the risk neutral formulation of the … Read more
Given an originally robust optimal decision and allowing perturbation parameters of the linear programming problem to run through a maximum uncertainty set controlled by a variable of perturbation radius, we do robust sensitivity analysis for the robust linear programming problem in two scenarios. One is to keep the original decision still robust optimal, the other … Read more
Perspective functions have long been used to convert fractional programs into convex programs. More recently, they have been used to form tight relaxations of mixed-integer nonlinear programs with so-called indicator variables. Motivated by a practical application (maximising energy efficiency in an OFDMA system), we consider problems that have a fractional objective and indicator variables simultaneously. … Read more
We consider a novel method entitled constraints reduction programming which aims to reduce the constraints in an optimization model. This method is derived from various applications of management or decision making, and has potential ability to handle a wider range of applications. Due to the high combinatorial complexity of underlying model, it is difficult to … Read more
In this work, we study the problem of scheduling courses and instructors in the Mathematics Department at the United States Naval Academy (USNA) in a resilient manner. Every semester, the department needs to schedule around 70 instructors and 150-180 course sections into 30 class periods and 30 rooms. We formulate a stochastic integer linear program … Read more
Despite recent interest in multiobjective integer programming, few algorithms exist for solving biobjective mixed integer programs. We present such an algorithm: the Boxed Line Method. For one of its variants, we prove that the number of single-objective integer programs solved is bounded by a linear function of the number of nondominated line segments in the … Read more